Radeon Software 16.6.2 is ready for the Radeon RX 480
 

In the unlikely event you're the new owner of a Radeon RX 480, AMD has a fresh batch of drivers for you. Radeon Software 16.6.2 adds support for the new card. It's also the first release of Radeon Software with AMD's new WattMan utility on board, a replacement for the older OverDrive overclocking and system monitoring suite.

http://techreport.com/news/30332/rad...-radeon-rx-480