It does to a point when it is easier to find higher FSB than low latency memory in terms of cost to performance.

My Corsair PC2700 CL2 runs with 3:2 ratio in P4 2.6C 865 Chipset with higher performance using 2-3-3-6 than running 5:4 ratio 3-4-4-8.

But, my ego tells me to show off at 5:4 or 1:1 ratio using the most relax timing. After the show off I quietly tightening the timing and reduce the ratio.