Microsoft tells IE faithful on Windows XP to avoid F1 key
 

Still hanging around on Windows XP? Perfectly acceptable. Still using Internet Explorer to browse the world wide web? Just a wee bit less forgivable, but we understand that some of you simply can't get around it. If we just rung your bell, you might want to rip the F1 key right off of your keyboard (at least temporarily), as a recently discovered vulnerability in VBScript -- which can only bother Windows 2000, Windows XP and Windows Server 2003 -- could allow malicious code to weasel its way right into your life with a single keystroke. As the story goes, some ill-willed web sites are encouraging users to smash the F1 key in order to access a Microsoft Help file, and when said key is depressed, "arbitrary code could be executed in the security context of the currently logged-on user."

http://www.engadget.com/2010/03/02/m...-avoid-f1-key/