Matrox M-series graphic cards go 4-up natively
 

Matrox just announced er, last week, it's new M-Series of graphics cards powered by the industry's first QuadHead GPU. All the PCIe X16 cards offer 512MB of graphics memory and support up to 4x widescreen monitors (DVI or analog) simultaneously as one large desktop or as independent resolutions. The cards can connect a pair of monitors at a max digital resolution of 2,560 x 1,600 or just 1,920 x 1,200 if you're looking to go quad. What, you're not still getting by with just a single display are you? Look for the M-series to go retail before September is through. (src: Engadget)

http://www.matrox.com/graphics/en/pr...corpo/mseries/